Magnesium L-Threonate, 270 capsules

$97,75
In stock

A highly effective, superior form of magnesium valued for its high absorption and availability in the brain and to cells in the body.

Detailed information

Product detailed description

Dr. Mercola Magnesium L-Threonate, a highly effective form of magnesium valued for its high absorption and availability in the brain and to cells in the body. Magnesium Threonate aids synaptic plasticity (related to learning, memory and cognitive function), increasing magnesium content in the brain by about 15% according to research, where other forms of magnesium struggle to reach. It also plays a role in the process of reducing brain aging.

Beware of the quality of the product, there is only one original!

Always look for the original logo on a product that actually contains Magtein's patented form of magnesium.

There are strict licensing rules associated with the patent and part of the license not only requires the logo to be included, but the recommended dosage must be the same per capsule for all manufacturers.

 

Magnesium L-threonate can be purchased as a raw material in China, it is generally referred to as C8H14MgO10 98-99% powder - it is definitely not Magtein but an imitation of it by Chinese manufacturers. The fact that it is a 98-99% copy does not guarantee the consistency and composition according to the patent, which has not yet been released and is purchased under pre-arranged conditions.

We are not saying that this is a priori wrong, anyone can buy whatever they want at will, but you need to beware and accept the risk in case you buy such a version.

Such a product should meet not only the microbiology but also the tests for the raw material, i.e. that it really is a magnesium threonate molecule in the concentration specified.

 

Why is magnesium important for our body?

Magnesium is ranked 4th as one of the most abundant minerals in the body. It is important for about 300 enzymatic reactions in the body. It is primarily found in the bones. It is also important for many physiological functions

Magnesium is the king of minerals, just as vitamin D is the king of vitamins.

Magnesium is responsible for the proper functioning of basic metabolic processes, including DNA synthesis, including replication, and muscle contraction. It plays a vital role in energy production, what we call ATP (adenosine triphosphate) is actually Mg-ATP. We must not forget that most biological enzymes catalyze the stress reaction using magnesium.

EFSA-approved claims:

Contributes to reducing the rate of fatigue and exhaustion.
Contributes to electrolyte balance.
Contributes to normal energy metabolism.
Contributes to the normal functioning of the nervous system.
Contributes to normal muscle function.
Contributes to normal protein synthesis.
Contributes to normal mental activity.
Contributes to the maintenance of normal bone health.
Magnesium contributes to the maintenance of normal dental health.
Contributes to the process of cell division.
What to watch out for when eating food?

Remember From a diet rich in Mg2+, 30-40% is absorbed. Thus, at 350 mg, about 105-140 mg (5mmol Mg2+) is available.

 

Examples of foods particularly rich in magnesium include (in order of magnesium content):

Food (100 grams) magnesium content (mg):

Seaweed, agar - 770 mg
Coriander leaf (spice) - 694 mg
Pumpkin seeds, dried - 535 mg
Cocoa, dry powder, unsweetened - 499 mg
Basil - 422 mg
Cumin seeds (spices) - 386 mg
Brazil nuts, dried - 376 mg
Parsley - 372 mg
Almond butter - 303 mg
Whey, sweet - 176 mg
Leeks - 156 mg
Cabbage, raw - 88 mg
Spinach - 79 mg
I prefer the above list of foods and deliberately do not list problematic sources, which in many cases act antagonistically (i.e., contain excessive minerals, phytates, and other substances that in turn block magnesium or directly compete for transport systems in the body). It is important to favour organic foods - chemical fertilisers and pesticides do not contribute to optimal magnesium levels in the soil.

 

For maximum magnesium supplement potential, do not combine with milk and ideally without the foods on the list below. This is because magnesium interferes with phosphorus and potassium:

A diet rich in phosphorus (meat and poultry, nuts, milk and legumes).
Diet rich in potassium (avocados, bananas, oranges, potatoes, dairy products and eggs).
Some other sources rich in magnesium, as many of you suspect, may not be satisfactory from a health point of view either, so there is no point in favouring them:

coffee
tea
nuts
legumes (phytates, phosphorus)
whole grain cereals
dairy products (problematic due to calcium content - antagonist)
tofu (if you eat soy, look for a fermented version of nigari - magnesium chloride is used in the manufacturing process to curdle soy milk)
cow's milk (calcium antagonist - interference at the muscle level during muscle contraction)

 

What about the bioavailability of magnesium in our bodies?

The recommended daily intake of magnesium ions for an adult male is about 400 mg and for a female about 300 mg, which on average corresponds to 15 mmol Mg2+.

The main organ where magnesium is absorbed is the small intestine, but it is also resorbed in the large intestine (GIT).

From a diet rich in Mg2+, 30-40% is absorbed. Thus, at 350 mg, the utilization is about 105-140 mg (5mmol Mg2+).

We must also not forget that 60-70% of magnesium ions are excreted in the stool, so it depends on the state of your intestines when resorbing magnesium (negative effects - malabsorption syndrome, celiac disease, chronic intestinal inflammation, cystic fibrosis and others).

Who is magnesium supplementation appropriate for?

 

In case you suspect:

Excessive stress factors (stress is involved in the excretion of magnesium from the body, high cortisol)
high blood pressure,
cramps in the lower limbs,
migraine, anxiety, irritability, depression,
heart disease (absolutely crucial for cardiovascular health, some doctors administer magnesium before certain surgeries),
unstable blood sugar levels,
insomnia
obesity problems
osteoporosis
diabetes (if you are insulin resistant, magnesium storage becomes a problem and starts to be excreted in the urine; deficiency affects energy production - magnesium depletion precedes insulin resistance)
restless legs syndrome
The recommended daily intake of magnesium ions is (equivalent to 15 mmol Mg2+ on average):

for an adult male approx. 400 mg
for an adult woman, approx. 300 mg.
For men over 31 years of age, approx. 420 mg per day, for women approx. 320 mg per day.

Benefits of the product and what is Magnesium L-threonate (Magtein)?

 

Magnesium L-threonate (MMFS-01 or Magtein™) is L-threonic acid combined with magnesium Mg2+.

Magtein is the only form that shows the ability to cross the blood-brain barrier.

Initial animal studies show that Magnesium L-threonate helps maintain neuronal cell health and increases neuronal plasticity. 

The most recent randomized double-blind study (including a placebo effect control) in humans was conducted in August 2016 (published in the Journal of Alzheimer's Disease). Magnesium L-threonate (MMFS-01) confirmed potential in improving cognitive function in older people.

Magnesium L-threonate shows promising potential in studies for:

increasing magnesium levels in the brain
improving short and long-term memory
as well as improving spatial perception and cognitive function.
Dr. Liu's tests show that magnesium L-threonate, once absorbed, reaches the brain better than other forms of magnesium and thus shows the best results.

 

Does old age really mean automatic memory loss?

Research shows that Magtein significantly helps synaptic plasticity (related to learning, memory and cognitive function). Magnesium threonate increases magnesium content in the brain by about 15% where other forms of magnesium are difficult to get to, according to previous research.

Different magnesium compounds differ significantly in their bioavailability and thus their ability to increase synaptic plasticity, which leads to increased memory and cognitive function.

Loss of synaptic plasticity in the brain is naturally related to aging (forgetfulness, fatigue, inability to respond quickly, etc.). With the right form of magnesium, scientists believe this process can be greatly mitigated. Some data in animal models are even more optimistic. 

In 2015, the team around Professor Guosong Liu (see below) studied patients from 50 to 70 years old and concluded that magnesium L-threonate supplementation helps to significantly reduce the aging process of the brain.

 

Magnesium is absolutely crucial for the brain.

Magnesium helps to regulate the formation of critical cell connections in the learning and memory centers of the brain. Magnesium ions control the electrical ion pathways in grey cells. The more signals they can transmit the greater the connection and the better the memory. 

Comparing the benefits of magnesium L-threonate (Magtein)

free of fillers, dyes and preservatives (magnesium stearate), also non GMO
2000 mg of Magtein in the recommended daily dose (the maximum dose available in supplements on the market), 144 mg of magnesium with high bioavailability
What forms of magnesium are used in supplements?

Magnesium glycinate - a chelated form of magnesium (commonly 14% elemental magnesium with Albion Magnesium it is 18%) - a good alternative, however not as effective as L-threonate
Magnesium oxide - a non-chelated form bound to an organic acid or fatty acid, contains about 60% elemental magnesium (absorption about 4%)
Magnesium chloride/lactate - contains approx. 12% elemental magnesium, however it is more effective than magnesium oxide
Magnesium sulphate/hydroxide - typical laxative, contains approx. 42% elemental magnesium
Magnesium carbonate/magnesium carbonate - also used for stomach acidity, contains approx. 29-45% elemental magnesium
Magnesium taurate - a combination of magnesium and an amino acid (taurine) 
Magnesium citrate - contains about 12% of elemental magnesium, similarly magnesium aspartate (absorption of both is up to 70%)
Magnesium orotate - about 7% elemental magnesium from the tablet
magnesium gluconate - approx. 6% of elemental magnesium from the tablet (absorption rate approx. 56%)
It is necessary to distinguish between the elemental magnesium content of the tablet and the absorption of this content by the organism.

 

Dr. Liu - helped develop the active ingredient Magtein™

Professor Guosong Liu, M.D., Ph.D. is President and Founder of the Center for Learning and Memory, School of Medicine, Tsinghua University, Beijing, China and Adjunct Professor, Center for Learning and Memory, University of Texas Austin.

 

Dr. Liu was a research scientist at MIT (Massachusetts Institute of Technology) for 10 years, assessing various magnesium compounds and their ability to increase magnesium levels in the brain.

Different magnesium compounds vary significantly in their bioavailability and thus their ability to increase synaptic plasticity, which leads to increased memory and cognitive function.

Dr. Liu reviews the biochemistry and signaling mechanisms that led to this novel development of cognitive function and the effect of magnesium L-threonate on Alzheimer's disease in animal models, as well as a recent study assessing magnesium levels in Alzheimer's patients.

 

Dr. Liu also helped develop Magtein and the magnesium L-threonate molecule. Magnesium L-threonate shows promising potential in studies for:

increasing magnesium levels in the brain
improving short and long-term memory
as well as improving spatial perception and cognitive function.
Dr. Liu's tests show that magnesium L-threonate, once absorbed, reaches the brain better than other forms of magnesium and thus shows the best results.

Dr. Liu is also working on a hypothesis showing a correlation between magnesium deficiency and the incidence of Alzheimer's disease. According to his findings, patients with the disease have low magnesium levels.

Dr. Mercola Magnesium Threonate 270 Capsules - Ingredients:

3 vegan capsules (2000 mg magnesium L-threonate) contain approximately 144 mg of essential magnesium

Magnesium L-threonate, microcrystalline and hydroxypropyl cellulose, ascorbyl palmitate (vitamin C), capsule (hyroxypropyl methyl cellulose)

Dosage: 3 capsules daily, 2 hours before bedtime, 2 hours after meals or on an empty stomach.

Pack of 270 capsules for 90 days.

Cautions:
This product has been marketed as a dietary supplement. This product has no approved medicinal properties and is not a drug and is not intended as a substitute for a varied diet. Do not exceed the recommended dosage. Keep out of reach of children. Minimum shelf life indicated on the packaging. The information provided here is not intended to increase the consumption and yield of the products. We do not encourage inappropriate, immoderate or unjustified use of the products. Always read the package leaflet carefully, the active ingredients and consult your doctor or pharmacist for the use of the products.

 

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